WebAs the role of leptin in energy balance in neonate is unknown, we investigated the effect of acute (2 h) and chronic (7 days) administration of leptin (100 microg/day) on thermoregulation and mitochondrial protein abundance in adipose tissue. The concentration of uncoupling protein (UCP)1 and voltag … WebA transport protein is located in the inner mitochondrial membrane that exports ATP and imports ADP, the adenine nucleotide carrier. The inorganic phosphate necessary for the …
Yeast Mitochondria Lacking the Phosphate Carrier/p32 Are …
WebMar 21, 2014 · The mitochondrial phosphate carrier (PiC) is a member of the solute carrier 25A family that has a critical role in OXPHOS, serving as the primary route for inorganic phosphate (Pi) import... WebJul 25, 1984 · The phosphate transport protein from beef heart mitochondria has been purified on a large scale by hydroxylapatite chromatography in the presence of sodium … fatigue with chest pain
Pharos : Target Details - SLC25A3
WebJan 4, 2008 · Unexpected role of the phosphate carrier in mitochondrial fragmentation. Mitochondrial carriers constitute a family of hexa-transmembrane proteins that … WebMar 1, 2024 · We demonstrated that the phosphate carrier (PiC) is the dominant mitochondrial Pi transporter responsible for high Pi-induced superoxide generation, osteogenic gene upregulation, and calcific... Phosphate carrier protein, mitochondrial is a protein that in humans is encoded by the SLC25A3 gene. The encoded protein is a transmembrane protein located in the mitochondrial inner membrane and catalyzes the transport of phosphate ions across it for the purpose of oxidative phosphorylation. There are two … See more The SLC25A3 gene is located on the q arm of chromosome 12 in position 23.1 and spans 8,376 base pairs. The gene has 9 exons and produces a 40.1 kDa protein composed of 362 amino acids. The encoded protein … See more The encoded protein (PHC) catalyzes the transport of phosphate from the cytosol into the mitochondrial matrix, either by proton See more The encoded protein interacts with PPIF; this interaction is impaired by CsA. See more • Dolce V, Fiermonte G, Messina A, Palmieri F (1992). "Nucleotide sequence of a human heart cDNA encoding the mitochondrial phosphate carrier". DNA Sequence. 2 (2): … See more Mutations in this gene can cause mitochondrial phosphate carrier deficiency (MPCD), a fatal disorder of oxidative phosphorylation. Symptoms include lactic acidosis, … See more • Solute carrier family See more friday night funkin mickey mouse mode