WebDec 2, 2002 · Here, we report the identification of two novel taurine-containing modified uridines (5-taurinomethyluridine and 5-taurinomethyl-2-thiouridine) in human and bovine mitochondrial tRNAs. Our work further revealed that these nucleosides are synthesized by the direct incorporation of taurine supplied to the medium. WebJan 9, 2024 · Defective Mitochondrial tRNA Taurine Modification Activates Global Proteostress and Leads to Mitochondrial Disease Authors
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WebDec 2, 2002 · Here, we report the identification of two novel taurine-containing modified uridines (5-taurinomethyluridine and 5-taurinomethyl-2-thiouridine) in human and … WebMar 31, 2024 · Taurine and the Applications in the Pharmacotherapy of Human Diseases explores the significance of taurine in the biology of mitochondria. It also explains its role as a pharmacological agent for treating different diseases. Readers will gain an insight into the crucial role it plays in human physiology and the benefits of taurine supplements ... history of irbs
The expanding world of tRNA modifications and their disease ... - Nature
WebMay 1, 2024 · 1. Introduction. Mitochondria play a key role in metabolism, and their impairments cause various diseases, ranging from specific mitochondrial disorders [1] … WebApr 15, 2024 · Chronic kidney disease (CKD) is a serious public health problem characterized by progressive kidney function loss leading to end-stage renal disease (ESRD) that demands dialysis or kidney ... WebFeb 1, 2024 · Fatty liver disease (FLD) is mainly characterized by the pathophysiological progression from simple hepatic steatosis to steatohepatitis, which has been increasing in incidence and has attracted much attention due to its risk of hepatocellular carcinoma. ... Jamshidzadehn A et al. indicated that taurine treatment decreased mitochondrial ... history of intestinal obstruction icd 10